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Leukemia News
December 12, 2018

Latest Headlines
updated 6:47am EST

More Leukemia News
December 12, 2018

New Strategies May Improve CAR-T Cell Therapy

Dec. 3, 2018 — Researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy (CAR-T cell therapy) in treating ... read more

New Research on Stem Cell Transplantation for Myeloid Cancers

Dec. 3, 2018 — Improving outcomes for patients with myeloid cancers who undergo stem cell transplantation is a focus of several studies being presented this ... read more

Newly Diagnosed AML in Older Adults: Results for Venetoclax

Nov. 28, 2018 — Clinical trial results show a 91 percent response rate to the combination of venetoclax with azacitidine in older adults newly diagnosed with acute myeloid leukemia (AML). Of 33 patients given ... read more

Helping Blood Cells Regenerate After Radiation Therapy

Oct. 24, 2018 — Researchers have devised a way to help blood cells regenerate faster, by stimulating a particular type of stem cell to secrete growth factors that help blood cell precursor cells differentiate into ... read more

Oct. 22, 2018 — Researchers have developed a promising targeted strategy to treat chemotherapy-resistant acute myeloid leukemia (AML) and a diagnostic test to determine which AML patients would most likely benefit ... read more

New Way to Determine Whether Metastatic Cancer Cells in Breast Cancer Patients Are Dormant or Soon to Turn Deadly

Oct. 16, 2018 — For the first time ever, researchers have identified a protein as a marker that can indicate whether a cancer patient will develop a recurrence of lethal, metastatic ... read more

Cancer Patients With Rare Deadly Brain Infection Treated Successfully With Off-the-Shelf Adoptive T-Cell Therapy

Oct. 10, 2018 — An emerging treatment known as adoptive T-cell therapy has proven effective in a Phase II clinical trial for treating progressive multifocal leukoencephalopathy (PML), a rare and often fatal brain ... read more

Targeting Abnormal Signals Suggests Novel Method to Treat a Rare Childhood Blood Disease

Oct. 9, 2018 — Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease. This proof-of-concept finding ... read more

New, Rare Mechanism for ALL to Relapse After CAR T Cell Therapy

Oct. 1, 2018 — A single leukemia cell, unknowingly engineered with the leukemia-targeting chimeric antigen receptor (CAR) lentivirus and infused back into a patient, was able to reproduce and cause a deadly ... read more

Doctors Issue Caution Over Missed Cancer Diagnoses Tied to Immune Disorder

Oct. 1, 2018 — Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH ... read more

Cancer Hijacks the Microbiome to Glut Itself on Glucose

Sep. 28, 2018 — A new study shows that leukemia actively undercuts the ability of normal cells to consume glucose, thus leaving more glucose available to feed its own ... read more

Lung Cancer Drug Could Be Repurposed to Target 'Zombie' Proteins Linked to Leukemia

Sep. 25, 2018 — A new study highlights how a clinically approved lung cancer drug could potentially be 'repurposed' to design new treatments for future cancer therapies. The research focuses on a protein ... read more

Sep. 25, 2018 — Two recent studies present a new approach for bone marrow donation and transplant that preclinical laboratory tests suggest could make the life-saving procedure safer and more effective for patients. ... read more

Protein Produced in Gut Could Stave Off Deadly Bone Marrow Transplant Complication

Sep. 24, 2018 — An antimicrobial protein found in the gut can stave off a common and highly lethal side effect of bone marrow transplants, researchers ... read more

Strategies to Protect Bone Health in Hematologic Stem Cell Transplant Recipients

Sep. 19, 2018 — A new review looks at the major factors affecting bone health in mematologic stem cell transplant recipients, and provides expert guidance for the monitoring, evaluation and treatment of bone loss in ... read more

New Combination Treatment Targets Pre-Leukemia Stem Cells

Sep. 12, 2018 — Omacetaxine (to block protein synthesis) with venetoclax (to block oxidative phosphorylation), was highly effective against CD123+ leukemia stem ... read more

Central Mystery of a Baffling High-Risk Leukemia Solved

Sep. 12, 2018 — Investigators have unraveled the origins and identified mutations associated with a perplexing form of acute leukemia. The landmark study appears today as an advance online publication in the journal ... read more

Findings Could Improve Treatment for Challenging Acute Leukemia in Children

Sep. 12, 2018 — Researchers have made important discoveries that could lead to better treatment for a rare blood cancer in children that has features of both leukemia and ... read more

DNA Test for Predicing Risk of Leukemia Relapse

Sep. 11, 2018 — The DNA-based test paves the way for precision medicine by giving leukemia patients personal disease prognosis based on mutation frequency in their cancer ... read more

Unexpected Cell Population Key to Blood Cancer Relapse

Sep. 10, 2018 — A study suggests that leukemia cells change in unique ways in response to chemotherapy allowing them to masquerade for a short time so they are able to start disease ... read more

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